International Conference on Autoimmunity October 13-14, 2016 Manchester, UK

ConferenceSeries Ltd invites all the participants from all over the world to attend "International Conference on Autoimmunity" October 13-14, 2016 Manchester UK. includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

Autoimmunity-2016 is to gathering people in academia and society interested in Autoimmunity to share the latest trends and important issues relevant to our field/subject area Autoimmunity Summit-2016 brings together the Global leaders in Autoimmunity and relevant fields to present their research at this exclusive scientific program, The Autoimmunity Conference hosting presentations from editors of prominent refereed journals, renowned and active investigators and decision makers in the field of Autoimmunity. World Autoimmunity-2016 Organizing Committee also invites Young investigators at every career stage to submit abstracts reporting their latest scientific findings in oral and poster sessions.

Track 1: Autoimmune Diseases

Autoimmunity is the process of Immune Responses of an organism against its own tissues and cells. Any disease that results from such an unusual immune response is termed an autoimmune disease. Prominent examples include Diabetes Mellitus type 1, Systemic lupus Erythematosus, Celiac disease, Sarcoidosis,  Sjögren's syndrome, Hashimoto's thyroiditis, Addison's Disease, Idiopathic Thrombocytopenic purpura, Graves' Disease, Rheumatoid Arthritis  ,Dermatomyositis, Churg-Strauss Syndrome, and  Polymyositis. Autoimmune diseases are very often treated with steroids.

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International Conference on Autoimmunity October 13-14, 2016 Manchester, UK; Immunology Conferences October 13-14, 2016 Manchester, UK; 2nd International Conference on Innate Immunity, July 21-22, 2016, BERLIN, GERMANY: International Conference on Mucosal Immunology July28-29, 2016 Melbourne, Australia: 5th European Immunology Conference, July 21-23,2016 Berlin, Germany : International Conference on Allergy, Asthma & Clinical Immunology September 14-15,2016 Amsterdam,Netherlands; International Conference on Tumor Immunology and Immunotherapy' during July 28-30, 2016 in Melbourne, Australia.

Track 2: Immunometabolism and Autoimmunity

Metabolism is necessary for pathogen defence and survival of life. In the Immune Mechanism & Immune Metabolism is essential for Pathogen degradation, by immune cells, time of immune metabolic process high level of signals pass to Immune cells to get stimulate and Immunometabolism process get start by central metabolic pathways and antibacterial immunity has revealed. But if similar antigen is present on host cell it altered immune response and starts demonstration of autoimmune response against host cell and Autoimmune Diseases. Metabolic inflammation acts as metabolic hazard sensors. Cytokines have an essential role in mediating the properties of chronic inflammation on target tissues,

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Track 3: Hypersensitivity and Autoimmunity

Hypersensitivity is unwanted responses produced by the ordinary immune system, including allergies and autoimmunity. These responses may be harmful, uncomfortable, painful or infrequently fatal. Hypersensitivity responses require a pre-sensitized state of the host. Hypersensitivity is unusual or pathologic immune reaction that is triggered by an immune response to repetitive exposure to an antigen. Hypersensitivity diseases include autoimmune syndromes, in which immune reactions are concentrating against self-antigens, and that result from excessive or uncontrolled responses to external antigens.

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Track 4: Autoimmune Treatment

For the Autoimmune diseases in market there is no specific treatment presented because of its self-nature, Treatments for autoimmune disease have conventionally been immunosuppressive, anti-inflammatory, and palliative dealing inflammation is unsafe in autoimmune treatment. Non-immunological therapies is widely used to indulgence Autoimmune Diseases, such as hormone replacement in Type 1 Diabetes Mellitus or Hashimoto's thyroiditis treat outcomes of the auto violent response, thus these are comforting treatments. Dietary manipulation limits the severity of celiac disease. Steroidal or NSAID treatment limits inflammatory response of many diseases. IVIG is used for GBS and CIDP. These are Specific immunomodulatory therapies, available in market.

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Track 5: Inherited Autoimmunity

The Autoimmune illnesses are passed from parents to children because of dominancy of allele and gene mutation, epidemiologic and Clinical indication that the data from inherited autoimmune disease are carry forward to next generation because of its self-assemble nature. Multiple number of genes has been connected which cause autoimmune illness in the human beings major histocompatibility complex primarily genes are responsible to cause Autoimmune Diseases. These genes also called the HLA. Sometimes ecological influences resemble with the hereditary susceptibility for generating autoimmune disease. A few such activates have been identified in Autoimmune research, in which including the drugs, specific Mutagenic chemicals, Biological factors, carcinogenic molecules, and family clustering, sometimes the nutritional elements also responsible for Autoimmune Disorder.

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 Track 6: Cytokine and Current Research

Cytokines are minor secreted proteins released by cells have a exact effect on the connections and interactions amongst cells. Cytokines are locally present in autoimmune lesions where they are produced by inflammation which causes autoimmune attack. Cytokines play prominent roles in inflammation and many diseases, cytokines are signal holder having function pass the signal from one cell to other cells in proper manner, the cytokines performance is important in Autoimmune Diseases because of hyperactive signalling by cytokines, which is non-specific and over stimulation of cells.

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Track7:Autoimmunity in Women

The majority of people living with autoimmune complaints are women, frequently those who are of childbearing age. autoimmune diseases, majority of these diseases are more common in women than in men an predictable 75% Because Women certainly have stronger inflammatory responses than men because of XX allele in female arrangements, inflammation plays an  important role in several autoimmune diseases, Autoimmune diseases attack in women three times more than men. Some Autoimmune diseases have an even complex incidence in women.

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Track 8: Pathophysiology and Autoimmunity

Physiological processes where by the useful changes causing from a particular disease called Pathophysiology. A normal immune system involves in the activation of B and T-cells after getting signal from cytokines of microphage and NK cell, and the immune cells undergo differentiation to produce antibodies and  plasma cells to destroy infection causing partials, subsequently in large amounts T-Cell and B-Cell get activated, the normal immune response is assumed to involve B and T cell responses to the same antigen, conformations on the surface of a molecule for B cells and pre-processed peptide fragments of proteins for T cells. Idiotype Cross-Reaction – Idiotypes are antigenic epitopes originate in the antigen-binding portion (Fab) of the immunoglobulin element.

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 Track 9: Autoimmunity and Malignancy

Cancers are a large family of autoimmune diseases which involve in abnormal cell growth of cell.  A cancer is a group of cells that have undergone unregulated growth and cause harmful effect, Cancer subdivided in two category malignant and benign tumor, malignant tumor show metastasis but benign tumor is not harmful as malignant tumor, in which metastasis occur, cancer is a group of diseases involving self-destroying Autoimmune Diseases, because of uncontrolled growth of self-cells.

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 Track 10: Bioinformatics and Autoimmunity

Bioinformatics is the application of technology of computer for management of biological data. Computers are used to store, gather, analyse and integrate genetic and biological information, which can then be applied to gene-based drug development and discovery.  Bioinformatics is an interdisciplinary playing field that develops software tools and methods for understanding biological data. Bioinformatics database mostly used in protein sequences, in Autoimmune Diseases by using different databases.

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Track 11: Autoimmunity and Transplantation

More than 10, 0000 patients have received an as treatment for a severe autoimmune disease. Transplantation (HSCT) has been used as a treatment for severe and therapy-refractory for autoimmune diseases. Allogeneic Transplant replaces the auto-reactive host immune system and failure of transplantation and graft-versus-autoimmunity effect seen in patient,

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 Track 12: Genetic Engineering & Therapeutics

To treat Autoimmune Diseases Genetic Engineering & Therapeutics is current research growing wildly in biological research aria, for proper treatment against self-Antigen and new drugs creation, Polyreactive Antibodies; Directed Evolution; Antibody Response; Antibodies in a complex environment;  knowledge-based design;and Polyspecificity; is current research going on in research institute.The interface between off-target toxicity; Cellular Immunity in Cancer; Antibody Therapy and Antibodies; Antibody Pharmacokinetics, Cardiometabolic ,Medicine, Optimizing Antibody formats for Immunotherapy,  Polyclonals, Bispecifics, these are top research Therapeutics in genetic engineering.

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