Pathophysiology and Autoimmunity

Physiological processes where by the useful changes causing from a particular disease called Pathophysiology. A normal immune system involves in the activation of B and T-cells after getting signal from cytokines of microphage and NK cell, and the immune cells undergo differentiation to produce antibodies and  plasma cells to destroy infection causing partials, subsequently in large amounts T-Cell and B-Cell get activated, the normal immune response is assumed to involve B and T cell responses to the same antigen, conformations on the surface of a molecule for B cells and pre-processed peptide fragments of proteins for T cells. Idiotype Cross-Reaction – Idiotypes are antigenic epitopes originate in the antigen-binding portion (Fab) of the immunoglobulin element.

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